Recombinant EGFRviii antibody

Catalog No. ABIN7829604

The Human Chimeric anti-EGFRviii antibody (Clone 2E12) (ABIN7829604) specifically detects EGFRviii in FACS. The antibody is reactive with Human samples.

Quick Overview for Recombinant EGFRviii antibody (ABIN7829604)

Target: EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))

Antibody Type: Recombinant Antibody

Fragment: Fc fragment

Reactivity: Human

Host: Human, Rabbit

Clonality: Chimeric

Conjugate: This EGFRviii antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 2E12

Product Details anti-EGFRviii Antibody

Purpose: Anti-EGFRVIII antibody(2E12), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1/100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for EGFRviii

Target: EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))

Alternative Name: EGFRVIII

Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

UniProt: P00533