Recombinant Glutamate Receptor 1 antibody (N-Term)

Catalog No. ABIN7830370

This Chicken Chimeric antibody specifically detects Glutamate Receptor 1 in WB, IHC, ELISA and ICC. It exhibits reactivity toward Rat.

Quick Overview for Recombinant Glutamate Receptor 1 antibody (N-Term) (ABIN7830370)

Target: Glutamate Receptor 1 (GLUR1)

Antibody Type: Recombinant Antibody

Reactivity: Rat

Host: Chicken, Mouse

Clonality: Chimeric

Conjugate: This Glutamate Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone: N355-1

Product Details anti-Glutamate Receptor 1 Antibody

Binding Specificity: AA 1-389, N-Term

Expression System: Mammalian cells

Purpose: Anti-GluA1/GluR1 Glutamate Receptor (N355/1) Recombinant Chicken Chimeric mAb

Cross-Reactivity (Details): Does not cross-react with GluR2

Predicted Reactivity: Human,Mouse

Characteristics: This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of clone N355/1 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone N355/1 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media.

Purification: Purified by affinity chromatography

Immunogen: Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1 (accession number P19490) produced recombinantly in E. Coli.

Isotype: IgY

Application Details

Application Notes: 1:250-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1X PBS, 0.05 % Sodium Azide pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 24 months

Target Details for Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Alternative Name: GluA1/GluR1 glutamate receptor

Background:

Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (GluA1)

Our chicken Anti-GluA1/GluR1 glutamate receptor recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone N355/1. It detects human, mouse, and rat GluA1/GluR1 glutamate receptor and is purified by affinity chromatography. It works in WB, IHC, ICC, ELISA.

Gria1 Glur1

Molecular Weight: 100 kDa

UniProt: P19490

Pathways: PI3K-Akt Signaling