Recombinant Glutamate Receptor 1 antibody (N-Term)

Catalog No. ABIN7830371

The Chicken Chimeric anti-Glutamate Receptor 1 antibody is suitable to detect Glutamate Receptor 1 in samples from Rat. It has been validated for WB, IHC, ELISA and ICC.

Quick Overview for Recombinant Glutamate Receptor 1 antibody (N-Term) (ABIN7830371)

Target: Glutamate Receptor 1 (GLUR1)

Antibody Type: Recombinant Antibody

Reactivity: Rat

Host: Chicken, Mouse

Clonality: Chimeric

Conjugate: This Glutamate Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Grade: Carrier-free

Clone: N355-1

Product Details anti-Glutamate Receptor 1 Antibody

Binding Specificity: AA 1-389, N-Term

Expression System: Mammalian cells

Purpose: Anti-GluA1/GluR1 Glutamate Receptor (N355/1) Recombinant Chicken Chimeric mAb (BSA and Azide free)

Cross-Reactivity (Details): Does not cross-react with GluR2

Predicted Reactivity: Human,Mouse

Characteristics: This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of clone N355/1 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone N355/1 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media and buffer exchanged into 1X PBS.

Purification: Purified by affinity chromatography

Immunogen: Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1 (accession number P19490) produced recombinantly in E. Coli.

Isotype: IgY

Application Details

Application Notes: 1:250-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 24 months

Target Details for Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Alternative Name: GluA1/GluR1 glutamate receptor

Background:

Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (GluA1)

Our chicken Anti-GluA1/GluR1 glutamate receptor carrier-free recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone N355/1. It detects human, mouse, and rat GluA1/GluR1 glutamate receptor and is purified by affinity chromatography. It works in WB, IHC, ICC, ELISA.

Gria1 Glur1

Molecular Weight: 100 kDa

UniProt: P19490

Pathways: PI3K-Akt Signaling