2B4 antibody (AA 151-250)

Catalog No. ABIN740730

Cited in 1 publication. The Rabbit Polyclonal anti-2B4 antibody (ABIN740730) specifically detects 2B4 in WB, ELISA, IF (cc), IF (p), ICC, IHC (p) and IHC (fro). The antibody is reactive with Human and Rat samples.

Quick Overview for 2B4 antibody (AA 151-250) (ABIN740730)

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 2B4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-2B4 Antibody

Binding Specificity: AA 151-250

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD244

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-2B4 antibody (ABIN740730)

Peiffer, Wang, Zimmerman, Ransom, Carmella, Kuo, Chen, Oshima, Huang, Hecht, Stoner: "Dietary Consumption of Black Raspberries or Their Anthocyanin Constituents Alters Innate Immune Cell Trafficking in Esophageal Cancer." in: Cancer immunology research, Vol. 4, Issue 1, pp. 72-82, (2016) (PubMed).

Target Details for 2B4

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Alternative Name: CD244

Background:

Synonyms: 2B4, NAIL, Nmrk, NKR2B4, SLAMF4, Natural killer cell receptor 2B4, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, h2B4, SLAM family member 4, Signaling lymphocytic activation molecule 4, CD244

Background: Modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.

Gene ID: 51744

UniProt: Q9BZW8