RPA1 antibody

Catalog No. ABIN7833814

The Rabbit Polyclonal anti-RPA1 antibody is suitable to detect RPA1 in samples from Saccharomyces cerevisiae. It has been validated for WB and IP.

Quick Overview for RPA1 antibody (ABIN7833814)

Target: RPA1 (Replication Protein A1, 70kDa (RPA1))

Reactivity: Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-RPA1 Antibody

Purpose: Anti-RFa1/Rpa1 | Replication factor protein 1 (Saccharomyces cerevisiae)

Cross-Reactivity (Details): Saccharomyces cerevisiae

Immunogen: Purified

Application Details

Application Notes: 1: 200 (IP), 1 : 2000 (WB)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Serum. Contains 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube

Storage: -20 °C

Storage Comment: Store at -20°C, make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Target Details for RPA1

Target: RPA1 (Replication Protein A1, 70kDa (RPA1))

Alternative Name: RFa1/Rpa1

Background: Rfa1 (Replication Factor A protein 1) as part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication.

Molecular Weight: 70.3 kDa

Gene ID: 851266

UniProt: P22336

Pathways: Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA