NRF2 antibody (pSer40)

Catalog No. ABIN7842063

This Rabbit Monoclonal antibody specifically detects NRF2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for NRF2 antibody (pSer40) (ABIN7842063)

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NRF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NRF2 Antibody

Binding Specificity: pSer40

Purpose: Rabbit monoclonal antibody to NRF2 (Phospho-S40)

Specificity: Recognizes endogenous levels of NRF2 protein only when phosphorylated at S40.

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding S40 of human NRF2 protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/50 - 1/100)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 50 mM Tris-Glycine ( pH 7.4), 0.15M NaCl, 50 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Target Details for NRF2

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Alternative Name: NFE2L2

Background: NRF2, Nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2, HEBP1, Nuclear factor erythroid derived 2 like 2

Gene ID: 4780

UniProt: Q16236

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling