Topoisomerase I antibody (Center)

Catalog No. ABIN7845703

The Rabbit Polyclonal anti-Topoisomerase I antibody is suitable to detect Topoisomerase I in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Topoisomerase I antibody (Center) (ABIN7845703)

Target: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Topoisomerase I antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Topoisomerase I Antibody

Binding Specificity: Center

Purpose: Rabbit polyclonal antibody to Topoisomerase 1

Specificity: Recognizes endogenous levels of Topoisomerase 1 protein.

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Topoisomerase 1. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Target Details for Topoisomerase I

Target: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Alternative Name: TOP1

Background: DNA topoisomerase 1, DNA topoisomerase I

Gene ID: 7150, 21969, 64550

UniProt: P11387

Pathways: Caspase Cascade in Apoptosis, Stem Cell Maintenance