Topoisomerase I antibody

Catalog No. ABIN7845705

This Rabbit Monoclonal antibody specifically detects Topoisomerase I in WB, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Topoisomerase I antibody (ABIN7845705)

Target: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Topoisomerase I antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Topoisomerase I Antibody

Purpose: Rabbit monoclonal antibody to Topoisomerase 1

Specificity: Recognizes endogenous levels of Topoisomerase 1 protein.

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: A synthetic peptide of human Topoisomerase I

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/50 - 1/100), IF/IC (1/50 - 1/100)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 50 mM Tris-Glycine ( pH 7.4), 0.15M NaCl, 50 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Target Details for Topoisomerase I

Target: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Alternative Name: TOP1

Background: DNA topoisomerase 1, DNA topoisomerase I

Gene ID: 7150, 21969, 64550

UniProt: P11387

Pathways: Caspase Cascade in Apoptosis, Stem Cell Maintenance