Topoisomerase II alpha antibody (pSer1106)

Catalog No. ABIN7845707

The Rabbit Polyclonal anti-Topoisomerase II alpha antibody (ABIN7845707) specifically detects Topoisomerase II alpha in WB and IHC. The antibody is reactive with Human, Mouse, Rat and Pig samples.

Quick Overview for Topoisomerase II alpha antibody (pSer1106) (ABIN7845707)

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Reactivity: Human, Mouse, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Topoisomerase II alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Topoisomerase II alpha Antibody

Binding Specificity: pSer1106

Purpose: Rabbit polyclonal antibody to Topoisomerase 2 alpha (Phospho-S1106)

Specificity: Recognizes endogenous levels of Topoisomerase 2 alpha protein only when phosphorylated at S1106.

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding S1106 of human Topoisomerase 2 alpha protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/50 - 1/200)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Target Details for Topoisomerase II alpha

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Alternative Name: TOP2A

Background: TOP2, DNA topoisomerase 2-alpha, DNA topoisomerase II alpha isozyme

Gene ID: 7153, 21973, 360243

UniProt: P11388

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases