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H2AFX antibody

H2AFX Reactivity: Human, Mouse, Rat, Cow, Dog, Pig WB, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN742065
  • Target See all H2AFX Antibodies
    H2AFX (H2A Histone Family, Member X (H2AFX))
    Reactivity
    • 162
    • 79
    • 58
    • 24
    • 24
    • 18
    • 16
    • 11
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Pig
    Host
    • 144
    • 19
    • 2
    Rabbit
    Clonality
    • 120
    • 45
    Polyclonal
    Conjugate
    • 109
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This H2AFX antibody is un-conjugated
    Application
    • 129
    • 47
    • 44
    • 39
    • 33
    • 26
    • 24
    • 19
    • 16
    • 10
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Cow, Dog, Human, Mouse, Pig, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Histone H2A
    Isotype
    IgG
    Top Product
    Discover our top product H2AFX Primary Antibody
  • Application Notes
    WB(1:100-500)
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    H2AFX (H2A Histone Family, Member X (H2AFX))
    Alternative Name
    Histone H2A.x (H2AFX Products)
    Background

    Synonyms: H2A histone family member X, Histone H2A.x, H2afx, H2a.x, H2ax, Hist5-2ax, H2A.X, H2A/X, H2AX, H2AFX, H2AX_HUMAN.

    Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008].

    Molecular Weight
    16kDa
    Gene ID
    3014
    Pathways
    Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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