Recombinant CBL antibody (pSer669)

Catalog No. ABIN7847092

The Rabbit Monoclonal anti-CBL antibody is suitable to detect CBL in samples from Human. It has been validated for WB.

Quick Overview for Recombinant CBL antibody (pSer669) (ABIN7847092)

Target: CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CBL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CBL Antibody

Binding Specificity: pSer669

Expression System: HEK-293 Cells

Purpose: Recombinant rabbit monoclonal antibody to c-CBL (Phospho-S669)

Specificity: Recognizes endogenous levels of c-CBL protein only when phosphorylated at S669

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding S669 of human c-CBL protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS, pH 7.4, containing 50 % glycerol, 0.2 % BSA and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Target Details for CBL

Target: CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

Alternative Name: CBL

Background: CBL2, RNF55, E3 ubiquitin-protein ligase CBL, Casitas B-lineage lymphoma proto-oncogene, Proto-oncogene c-Cbl, RING finger protein 55, Signal transduction protein CBL

Gene ID: 867

UniProt: P22681

Pathways: TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals