D-Dimer antibody

Catalog No. ABIN7849756

The Mouse Monoclonal anti-D-Dimer antibody is suitable to detect D-Dimer in samples from Human. It has been validated for ELISA, WB and LF.

Quick Overview for D-Dimer antibody (ABIN7849756)

Target: D-Dimer

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This D-Dimer antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Lateral Flow (LF)

Clone: C9

Product Details anti-D-Dimer Antibody

Purpose: Monoclonal Anti-D-dimer (Capture Ab)

Specificity: It specifically recognize human D-dimer antigen, and does not cross react with BSA andfibrinogen.

Characteristics: This antibody may be used as Capture Ab in antibody pair experiments such as ELISA.

Purification: Protein A or G purified

Purity: >95 % by HPLC & SDS-PAGE

Immunogen: Human D-dimer protein.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01 M PBS ( pH 7.4) without preservative.

Preservative: Without preservative

Handling Advice: Avoid repeated freeze and thaw cycles.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for D-Dimer

Target: D-Dimer

Background: D-dimer is a fibrin degradation product (or FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two crosslinked D fragments of the fibrin protein. The D-dimer antigen is a unique marker of fibrin degradation that is formed by the sequential action of 3 enzymes: thrombin, factor XIIIa, and plasmin. Its concentration may be determined by a blood test to help diagnose thrombosis. Since its introduction in the 1990s, it has become an important test performed in patients suspected of thrombotic disorders. While a negative result practically rules out thrombosis, a positive result can indicate thrombosis but does not rule out other potential causes. Its main use, therefore, is to exclude thromboembolic disease where the probability is low. In addition, it is used in the diagnosis of the blood disorder disseminated intravascular coagulation.