Lipocalin 2 antibody

Catalog No. ABIN7849772

The Mouse Monoclonal anti-Lipocalin 2 antibody (Clone H11) (ABIN7849772) specifically detects Lipocalin 2 in WB, ELISA and LF. The antibody is reactive with Human samples.

Quick Overview for Lipocalin 2 antibody (ABIN7849772)

Target: Lipocalin 2 (LCN2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lipocalin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Lateral Flow (LF)

Clone: H11

Product Details anti-Lipocalin 2 Antibody

Purpose: Monoclonal Anti-NGAL (Capture Ab)

Specificity: It specifically recognize the human NGAL.

Characteristics: This antibody may be used as Capture Ab in antibody pair experiments such as ELISA.

Purification: Protein A or G purified

Purity: >95 % by HPLC & SDS-PAGE

Immunogen: Recombinant human NGAL.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01 M PBS ( pH 7.4) without preservative.

Preservative: Without preservative

Handling Advice: Avoid repeated freeze and thaw cycles.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for Lipocalin 2

Target: Lipocalin 2 (LCN2)

Alternative Name: NGAL

Background: Lipocalin-2 (LCN2), also known as oncogene 24p3 or neutrophil gelatinase-associated lipocalin (NGAL), is a protein associated with neutrophil gelatinase. The 25-kD LCN2 protein is believed to bind small lipophilic substances such as bacteria-derived lipopolysaccharide (LPS) and formylpeptides and may function as a modulator of inflammation. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor.

Pathways: Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis