Verified
WFDC2
Reactivity: Human
ELISA, IHC
Host: Goat
Polyclonal
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Buffer
0.9 % NaCl without preservative.
Preservative
Without preservative
Handling Advice
Avoid repeated freeze and thaw cycles.
Storage
-20 °C
Storage Comment
Aliquot and store at -20°C for long term (at least one year). Avoid repeated freeze and thaw cycles.
Expiry Date
12 months
Target
WFDC2
(WAP Four-Disulfide Core Domain 2 (WFDC2))
Alternative Name
HE4
Background
WAP four-disulfide core domain protein 2 - also known as Human Epididymis Protein (HE4) - is a protein that in humans is encoded by the WFDC2 gene.HE4 is a tumor marker of ovarian cancer, with 80 % sensitivity at a cut-off of 150 pmol/L. This gene encodes a protein that is a member of the WFDC domain family. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.