Recombinant GSTP1 antibody (AA 19-206)

Catalog No. ABIN7865545

This Rabbit Monoclonal antibody specifically detects GSTP1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant GSTP1 antibody (AA 19-206) (ABIN7865545)

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GSTP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: GSTP1-12956R

Product Details anti-GSTP1 Antibody

Binding Specificity: AA 19-206

Expression System: CHO Cells

Purpose: Recombinant Glutathione S-Transferase Pi1 (GSTP1) Antibody

Specificity: Glutathione S-transferases (GSTs) function in the metabolic detoxification of various environmental carcinogens and lipid hydroperoxides. In response to oxidative stress, upregulation of the GST family member GSTP1 occurs, consistent with this function. Furthermore, the GSTP1 gene is subject to CpG island hyper-methylation, a state that correlates with human prostatic carcinogenesis. GSTP1 gene hyper-methylation can be detected in urine, ejaculate and plasma from men with prostate cancer, potentially making GSTP1 a useful biomarker for prostate cancer screening.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Recombinant fragment (around aa19-206) of human full-length GSTP1 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for GSTP1

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Alternative Name: Glutathione S-Transferase Pi1

Background:

FAEES3, GST3, GSTP1, Glutathione S-transferase P, GST class-pi, GSTP1-1

Human brain, lung, placenta or liver.

Molecular Weight: 23kDa

Gene ID: 2950

UniProt: P09211

Pathways: Cellular Response to Molecule of Bacterial Origin