Recombinant ADRP antibody (AA 249-376)

Catalog No. ABIN7863926

The Mouse Monoclonal anti-ADRP antibody (Clone rADFP-9321) (ABIN7863926) specifically detects ADRP in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant ADRP antibody (AA 249-376) (ABIN7863926)

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADRP antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: RADFP-9321

Product Details anti-ADRP Antibody

Binding Specificity: AA 249-376

Expression System: CHO Cells

Purpose: Recombinant Adipophilin / Perilipin-2 (Marker of Lipid Accumulation) Antibody

Specificity: Recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Recombinant fragment (around aa 249-376) of human Adipophilin (ADFP) protein (exact sequence is proprietary)

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for ADRP

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Alternative Name: Adipophilin

Background:

Adipophilin, ADFP, Adipose differentiation-related protein (ADRP), Perilipin-2 (PLIN2)

adrenal gland or cerebellum (IHC).|liver

Molecular Weight: 48kDa

Gene ID: 123, 3416

UniProt: Q99541

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism