Recombinant C9 antibody (C-Term)

Catalog No. ABIN7865484

This Mouse Monoclonal antibody specifically detects C9 in IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant C9 antibody (C-Term) (ABIN7865484)

Target: C9 (Complement Component C9 (C9))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This C9 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: R10A6

Product Details anti-C9 Antibody

Binding Specificity: C-Term

Expression System: CHO Cells

Purpose: Recombinant Complement Component C9 (CCC9) (Early Myocardial Infarction Marker) Antibody

Specificity: Complement component C9 binds to the C5b-8 complex as the final protein of the membrane attack complex. After binding, it undergoes a conformational change and inserts itself into the cell membrane, forming transmembrane channels. Complement component C9 acts in a similar way to perforin, a pore forming protein found in cytotoxic T cells. Male and female reproductive tissues express and synthesize complement components, binding proteins and receptors, although the implications of this are unclear.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Prokaryotic recombinant protein corresponding to a C-terminal region of the complement component C9 molecule.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for C9

Target: C9 (Complement Component C9 (C9))

Alternative Name: Complement Component C9

Background:

Complement component C9a | Complement component C9b

Human liver, placenta, myocardium or rejected renal transplant tissue.

Molecular Weight: 71kDa

Gene ID: 735

UniProt: P02748

Pathways: Complement System