Recombinant Cathepsin G antibody (N-Term)

Catalog No. ABIN7857710

This Mouse Monoclonal antibody specifically detects Cathepsin G in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant Cathepsin G antibody (N-Term) (ABIN7857710)

Target: Cathepsin G (CTSG)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cathepsin G antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: R19C3

Product Details anti-Cathepsin G Antibody

Binding Specificity: N-Term

Expression System: CHO Cells

Purpose: Recombinant Cathepsin G (Neutrophil Marker) Antibody

Specificity: Cathepsins are members of the papain family of cysteine proteases which are involved in a variety of physiological processes such as proenzyme activation, enzyme inactivation, antigen presentation, hormone maturation, tissue remodeling and bone matrix resorption. Cathepsin G is a 29 kD serine protease and is located in neutrophilic polymorphonuclear leukocytes which contain specialized azurophil granules together with two other serine proteases, elastase and protease 3. These three proteases may participate in the killing and digestion of engulfed pathogens and in connective tissue remodeling at sites of inflammation. Cathepsin G has also been found to be essential for the induction of human natural killer cell cytotoxicity.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Prokaryotic recombinant protein corresponding to a 124 amino acid N-terminal region of the cathepsin G molecule

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Cathepsin G

Target: Cathepsin G (CTSG)

Alternative Name: Cathepsin G

Background:

CATG

THP-1 cells. Human bone marrow or lymphoid tissue.

Molecular Weight: 32kDa

Gene ID: 1511

UniProt: P08311

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones