Recombinant CEACAM6 antibody

Catalog No. ABIN7865530

This Rabbit Monoclonal antibody specifically detects CEACAM6 in WB, IHC, ELISA, FACS and Func. It exhibits reactivity toward Human.

Quick Overview for Recombinant CEACAM6 antibody (ABIN7865530)

Target: CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CEACAM6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Functional Studies (Func)

Clone: CEACAM6-13371R

Product Details anti-CEACAM6 Antibody

Expression System: CHO Cells

Purpose: Recombinant CEACAM6 / CD66c / CEA (Pancreatic Adenocarcinoma Biomarker) Antibody

Specificity: The CD66 (also designated carcinoembryonic antigen, CEA, biliary glycoprotein I, BGP-1, CEACAM) immunoglobulin superfamily of genes encode cell adhesion proteins, which are expressed at higher levels in tumorous tissues than in normal tissues. CD66 mRNA is strongly expressed in primary colon tumors and, to a lesser extent, in normal colonic tissue. The human CD66 gene family is a diverse set of glycoproteins of epithelial and hematopoietic lineage that comprises 29 genes, which map to chromosome position 19q13.1-q13.2. CD66A, CD66B, CD66C, CD66D, CD66E and CD66F are the best characterized CD66 antigens, and CD66A-D expression upregulates on the surface of granulocytes upon stimulation. Certain CD66 isoforms mediate homotypic and heterotypic intercellular adhesion events independently of cell type.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Recombinant CEACAM6 protein

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CEACAM6

Target: CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))

Alternative Name: CEACAM6

Background:

CEACAM6, NCA, CD66c

Human appendix, colon or pancreatic cancer. HT-29 or AsPC-1.

Molecular Weight: 90kDa

Gene ID: 4680

UniProt: P40199