Recombinant HCV NS3 antibody

Catalog No. ABIN7857795

The Mouse Monoclonal anti-HCV NS3 antibody is suitable to detect HCV NS3 in samples from Human. It has been validated for IHC.

Quick Overview for Recombinant HCV NS3 antibody (ABIN7857795)

Target: HCV NS3 (Hepatitis C Virus NS3 (HCV NS3))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HCV NS3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: RMMM33

Product Details anti-HCV NS3 Antibody

Expression System: CHO Cells

Purpose: Recombinant Hepatitis C virus NS3 (Nonstructural protein 3) Antibody

Specificity: Non structural protein 3 (NS3) of hepatitis C virus (HCV) is a protein of 67 to 70 kD that contains at least three enzymatic activities, a protease, a serine protease and an RNA helicase. NS3 is produced as part of a polyprotein of about 3000 amino acids which is encoded by the viral genome. This polyprotein undergoes proteolytic processing by a combination of cellular and viral proteases, including those provided by NS3, to yield all of the mature viral proteins. The RNA helicase activity of NS3 is thought to be involved in viral replication.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Prokaryotic recombinant protein corresponding to non-structural protein 3 of hepatitis C virus, strain 1b

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for HCV NS3

Target: HCV NS3 (Hepatitis C Virus NS3 (HCV NS3))

Alternative Name: Hepatitis C virus NS3

Target Type: Viral Protein

Background:

NS3, NS3P, Serine protease/NTPase/helicase, p70

Hepatitis C infected tissue or cells.

Molecular Weight: 70kDa

UniProt: P27958