Recombinant Selectin E/CD62e antibody

Catalog No. ABIN7857825

The Mouse Monoclonal anti-Selectin E/CD62e antibody is suitable to detect Selectin E/CD62e in samples from Human. It has been validated for IHC.

Quick Overview for Recombinant Selectin E/CD62e antibody (ABIN7857825)

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Selectin E/CD62e antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: R16G4

Product Details anti-Selectin E/CD62e Antibody

Expression System: CHO Cells

Purpose: Recombinant CD62E / Selectin E (SELE) / ELAM-1 Antibody

Specificity: CD62E is also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) or E-selectin. It is a type I membrane protein that belongs to the selectin family of surface molecules (along with CD62L and CD62P). CD62E is expressed on cytokine induced endothelial cells and mediates their binding to leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial tethering and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues. The main ligands recognized by CD62E are oligosaccharides related to sialyl-lewis X.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Prokaryotic recombinant fusion protein corresponding to the cysteine-rich complement control protein domains of the CD62E molecule

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for Selectin E/CD62e

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Alternative Name: CD62E

Background:

CD62E, ELAM1, SELE, E-selectin, ELAM-1, LECAM2

Human bone marrow, lymph node, inflamed tonsil, heart or liver.

Molecular Weight: 115kDa

Gene ID: 6401

UniProt: P16581

Pathways: Thromboxane A2 Receptor Signaling