Recombinant SALL4 antibody (AA 1-185)

Catalog No. ABIN7863301

The Rabbit Monoclonal anti-SALL4 antibody is suitable to detect SALL4 in samples from Human. It has been validated for IHC.

Quick Overview for Recombinant SALL4 antibody (AA 1-185) (ABIN7863301)

Target: SALL4 (Sal-Like 4 (SALL4))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SALL4 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: SALL4-7301R

Product Details anti-SALL4 Antibody

Binding Specificity: AA 1-185

Purpose: Recombinant SALL-4 (Metastatic Germ Cell Tumor Marker) Antibody

Specificity: Sall3 (SALL3, sal-like 3) and Sall4 (SALL4, sal-like 4) are mammalian homologs of the Drosophila region-specific homeotic gene spalt, which encodes a zinc finger-containing transcription regulator. Drosophila spalt is an essential genetic component required for the specification of posterior head and anterior tail as opposed to trunk. Sall3 is expressed at 24 weeks of gestation in several regions of the human fetal brain including neurons of the hippocampus formation and of mediodorsal and ventrolateral thalamic nuclei, Purkinje cells of the cerebellum, and a subset of neurons in the brainstem. Sall4 expression in early mouse embryos is gradually confined to the head region and the primitive streak, followed by prominent expression in the developing midbrain, branchial arches, limbs and genital papilla.

Purification: 200ug/ml of Ab purified by Protein A Column.

Immunogen: Recombinant fragment (around aa1-185) of human MIC2 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for SALL4

Target: SALL4 (Sal-Like 4 (SALL4))

Alternative Name: SALL-4

Background:

DRRS, HSAL4, Sal like 4 (Drosophila), Sal like Protein 4, Sall4, Spalt like transcription factor 4, Tex20, Zinc finger protein 797, Zinc finger protein SALL4, ZNF797

Human testis, seminoma or ovary.

Molecular Weight: 165 / 95 kDa (A isoform / B isoform)

Gene ID: 57167, 517113

UniProt: Q9UJQ4

Pathways: Stem Cell Maintenance, Tube Formation