Recombinant Cadherin-16 antibody

Catalog No. ABIN7863925

The Mouse Monoclonal anti-Cadherin-16 antibody is suitable to detect Cadherin-16 in samples from Human. It has been validated for IHC.

Quick Overview for Recombinant Cadherin-16 antibody (ABIN7863925)

Target: Cadherin-16 (CDH16)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cadherin-16 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: RCDH16-7342

Product Details anti-Cadherin-16 Antibody

Purpose: Recombinant Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Antibody

Specificity: This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ç 79oΩKsp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Purification: 200ug/ml of Ab purified by Protein A.

Immunogen: Recombinant human full-length CDH16 protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Cadherin-16

Target: Cadherin-16 (CDH16)

Alternative Name: Ksp-Cadherin

Background:

Cadherin-16 (CDH16), Kidney-specific cadherin, Ksp-cadherin antibody

Normal kidney or renal cell carcinoma.

Molecular Weight: 130kDa

Gene ID: 1014, 513660

UniProt: O75309