Recombinant CNN1 antibody (C-Term)

Catalog No. ABIN7862652

The Rabbit Monoclonal anti-CNN1 antibody is suitable to detect CNN1 in samples from Human. It has been validated for IHC.

Quick Overview for Recombinant CNN1 antibody (C-Term) (ABIN7862652)

Target: CNN1 (Calponin 1 (CNN1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CNN1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: CNN1-4227R

Product Details anti-CNN1 Antibody

Binding Specificity: C-Term

Purpose: Recombinant Calponin-1 (Smooth Muscle Marker) Antibody

Specificity: Calponin a 33 kDa polypeptide, is a cytoskeleton-associated actin-binding protein that also interacts tropomyosin and calmodulin. Calponin antibody has been found to be useful as a marker for myoepithelial and basal lamina in differentiating microinvasive from in situ ductal carcinomas of the breast. Calponin antibody may also have applications in malignant myoepithelium and pleomorphic adenoma of salivary gland as well as a useful marker for fine needle aspirates of papillary breast lesions. The antibody has been found in tissue extracts from smooth muscle, but not in fibroblast extracts.

Purification: 200ug/ml of Ab purified by Protein A/G.

Immunogen: Synthetic peptide corresponding to residues on the C-terminus of human Calponin was used as an immunogen

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CNN1

Target: CNN1 (Calponin 1 (CNN1))

Alternative Name: Calponin-1

Background:

Calponin 1 basic smooth muscle, Calponin H1 smooth muscle, Calponin-1, CNN1, Cnn1, Sm Calp, SMCC

K562 cells. Myoepithelial cells in breast ducts or leiomyosarcoma.

Molecular Weight: 33kDa

Gene ID: 1264, 465929

UniProt: P51911