Recombinant CNN1 antibody (C-Term)

Catalog No. ABIN7858025

This Rabbit Monoclonal antibody specifically detects CNN1 in IHC and WB. It exhibits reactivity toward Human.

Quick Overview for Recombinant CNN1 antibody (C-Term) (ABIN7858025)

Target: CNN1 (Calponin 1 (CNN1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CNN1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: CNN1-8870R

Product Details anti-CNN1 Antibody

Binding Specificity: C-Term

Purpose: Recombinant Calponin-1 (Smooth Muscle Marker) Antibody

Specificity: Calponin a 33 kDa polypeptide, is a cytoskeleton-associated actin-binding protein that also interacts tropomyosin and calmodulin.Calponin antibody has been found to be useful as a marker for myoepithelial and basal lamina in differentiating microinvasive from in situ ductal carcinomas of the breast. Calponin antibody may also have applications in malignant myoepithelium and pleomorphic adenoma of salivary gland as well as a useful marker for fine needle aspirates of papillary breast lesions. The antibody has been found in tissue extracts from smooth muscle, but not in fibroblast extracts.

Purification: 200ug/ml of Ab purified by Protein A/G.

Immunogen: Recombinant fragment corresponding to C-terminus of human Calponin (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for CNN1

Target: CNN1 (Calponin 1 (CNN1))

Alternative Name: Calponin-1

Background:

Calponin 1 basic smooth muscle, Calponin H1 smooth muscle, Calponin-1, CNN1, Cnn1, Sm Calp, SMCC

K562 cells. Myoepithelial cells in breast ducts, colon or leiomyosarcoma. intestine, Lung

Molecular Weight: 33kDa

Gene ID: 1264, 465929

UniProt: P51911