Recombinant BCL2L1 antibody (AA 1-100)

Catalog No. ABIN7863346

This Rabbit Monoclonal antibody specifically detects BCL2L1 in IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant BCL2L1 antibody (AA 1-100) (ABIN7863346)

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BCL2L1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: BCL2L1-4509R

Product Details anti-BCL2L1 Antibody

Binding Specificity: AA 1-100

Purpose: Recombinant Bcl-X (Apoptosis Marker) Antibody

Specificity: Recognizes a protein of 27 kDa, identified as the Bcl-X protein. This MAb shows no cross-reaction with Bcl-2°™ or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241-amino acid protein which suppresses cell death. And Bcl-XS (short), a 178-amino acid protein lacking a 63-amino acid domain which functions as a dominant inhibitor of Bcl-2.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-100) of human BCL2L1 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for BCL2L1

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Alternative Name: Bcl-X

Background:

Apoptosis regulator Bcl-X, B cell lymphoma 2 like, BCL XL/S, Bcl-2-like protein 1, Bcl2-L-1, BCL2L, Bcl2l1, BCLX, BclXL, BclXs, Protein phosphatase 1 regulatory subunit 52 (PPP1R52)

HL-60 or HeLa cells. Reed-Sternberg cells in Hodgkin s lymphoma., Jurkat, K562

Molecular Weight: 27kDa

Gene ID: 598, 516966

UniProt: Q07817

Pathways: Apoptosis, Negative Regulation of intrinsic apoptotic Signaling