FSHB antibody (AA 1-100)

Catalog No. ABIN7864715

This Mouse Monoclonal antibody specifically detects FSHB in IHC. It exhibits reactivity toward Human.

Quick Overview for FSHB antibody (AA 1-100) (ABIN7864715)

Target: FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FSHB antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: FSHB-6845

Product Details anti-FSHB Antibody

Binding Specificity: AA 1-100

Purpose: FSH-beta (Follicle Stimulating Hormone-beta) Antibody

Specificity: Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-100) of human FSHB (exact sequence is proprietary)

Isotype: IgG3, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for FSHB

Target: FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))

Alternative Name: FSH-beta

Background:

Follicle stimulating hormone beta polypetide, Follicle stimulating hormone beta subunit, Follitropin beta chain, Follitropin subunit beta, FSH-B, FSH-beta, FSHB, FSHbeta

Human anterior pituitary gland.

Molecular Weight: 22kDa

Gene ID: 2488, 36975

Pathways: Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process