s100a4 antibody (AA 1-101)

Catalog No. ABIN7858133

This Mouse Monoclonal antibody specifically detects s100a4 in IHC and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for s100a4 antibody (AA 1-101) (ABIN7858133)

Target: s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This s100a4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: S100A4-7097

Product Details anti-s100a4 Antibody

Binding Specificity: AA 1-101

Purpose: S100A4 / Metastasin / Calvasculin (Marker of Tumor Metastasis) Antibody

Specificity: S100A4 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100 genes include at least 25 members, including S100A1-S100A18, trichohyalin, filaggrin, repetin, S100P, and S100Z. S100A4 exerts its function via direct interaction with a number of proteins including P53, P63, non-muscle myosin IIA, ±6≤4 integrin, and liprin b1. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 1-101) of human S100A4 protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for s100a4

Target: s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))

Alternative Name: S100A4

Background:

S100A4, S100 calcium-binding protein A4, Calvasculin, CAPL, Fibroblast specific protein 1 (FSP1), Leukemia multidrug resistance associated protein, Malignant transformation suppression 1 (MTS1), Metastasin, Placental calcium-binding protein

HeLa, PANC-1, A549 or A375 cells. Human placenta.

Molecular Weight: 10-12kDa

Gene ID: 6275, 654444

UniProt: P26447

Pathways: S100 Proteins