CLPS antibody (AA 1-112)

Catalog No. ABIN7865237

The Mouse Monoclonal anti-CLPS antibody (Clone CLPS-9898) (ABIN7865237) specifically detects CLPS in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for CLPS antibody (AA 1-112) (ABIN7865237)

Target: CLPS (Colipase, Pancreatic (CLPS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CLPS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: CLPS-9898

Product Details anti-CLPS Antibody

Binding Specificity: AA 1-112

Purpose: Colipase / CLPS Antibody

Specificity: The lipase gene family belongs to one of the most robust genetic superfamilies found in living organisms, which includes esterases and thioesterases. Members of the AB hydrolase subfamily include Hepatic Lipase (HL), Endothelial Lipase (EL), Lipoprotein Lipase (LPL), Pancreatic Lipase (PL), Gastric Lipase (GL) and LCAT. These family members play a crucial role in the metabolism of lipids. Pancreatic lipase, also designated pancreatic triacylglycerol acyl hydrolase, is important for dietary fat absorption as it hydrolyses triglycerides into diglycerides, monoglycerides and free fatty acids. Colipase, also known as CLPS or pancreatic colipase preproprotein, is a 112 amino acid secreted protein that functions as a cofactor of pancreatic lipase. Necessary for dietary lipid hydrolysis and localizing to pancreatic acinar cells, colipase allows pancreatic lipase to anchor itself to the lipid-water interface of lipid micelles, thereby preventing intestinal bile salts from washing it off.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-112) of human CLPS protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for CLPS

Target: CLPS (Colipase, Pancreatic (CLPS))

Alternative Name: Colipase

Background:

COL_HUMAN, Colipase, Colipase pancreatic, Pancreatic colipase preproprotein

Human pancreas, breast cancer or esophagus cancer.

Molecular Weight: 12kDa

Gene ID: 1208, 1340

UniProt: P04118

Pathways: Lipid Metabolism