Fatty Acid Binding Protein antibody (AA 1-127)

Catalog No. ABIN7858194

The Mouse Monoclonal anti-Fatty Acid Binding Protein antibody is suitable to detect Fatty Acid Binding Protein in samples from Human. It has been validated for IHC.

Quick Overview for Fatty Acid Binding Protein antibody (AA 1-127) (ABIN7858194)

Target: Fatty Acid Binding Protein (FABP)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fatty Acid Binding Protein antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: FABP1-3484

Product Details anti-Fatty Acid Binding Protein Antibody

Binding Specificity: AA 1-127

Purpose: Fatty Acid Binding Protein (Liver) / FABP1 Antibody

Specificity: Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Human recombinant FABP1 protein fragment (around aa1-127) (exact sequence is proprietary)

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Fatty Acid Binding Protein

Target: Fatty Acid Binding Protein (FABP)

Alternative Name: Fatty Acid Binding Protein

Background:

FABP1, L-FABP

Liver or colon carcinoma tissues (IHC).

Molecular Weight: 14kDa

Gene ID: 2168, 380135

UniProt: P07148

Pathways: Chromatin Binding, Monocarboxylic Acid Catabolic Process