Fatty Acid Binding Protein antibody (AA 1-127)

Catalog No. ABIN7858195

The Mouse Monoclonal anti-Fatty Acid Binding Protein antibody (Clone FABP1-3485) (ABIN7858195) specifically detects Fatty Acid Binding Protein in IHC and WB. The antibody is reactive with Human samples.

Quick Overview for Fatty Acid Binding Protein antibody (AA 1-127) (ABIN7858195)

Target: Fatty Acid Binding Protein (FABP)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fatty Acid Binding Protein antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: FABP1-3485

Product Details anti-Fatty Acid Binding Protein Antibody

Binding Specificity: AA 1-127

Purpose: Fatty Acid Binding Protein (Liver) / FABP1 Antibody

Specificity: Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Human recombinant FABP1 protein fragment (around aa1-127) (exact sequence is proprietary)

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Fatty Acid Binding Protein

Target: Fatty Acid Binding Protein (FABP)

Alternative Name: Fatty Acid Binding Protein

Background:

FABP1, L-FABP

Liver or colon carcinoma tissues (IHC). Human kidney tissue lysate (WB).

Molecular Weight: 14kDa

Gene ID: 2168, 380135

UniProt: P07148

Pathways: Chromatin Binding, Monocarboxylic Acid Catabolic Process