LGALS13 antibody (AA 1-139)

Catalog No. ABIN7858252

The Mouse Monoclonal anti-LGALS13 antibody (Clone PP13-8897) (ABIN7858252) specifically detects LGALS13 in IHC. The antibody is reactive with Human samples.

Quick Overview for LGALS13 antibody (AA 1-139) (ABIN7858252)

Target: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LGALS13 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: PP13-8897

Product Details anti-LGALS13 Antibody

Binding Specificity: AA 1-139

Purpose: Galectin-13 (GAL13) / Placental Protein 13 (PP13) Antibody

Specificity: It recognizes a 32 kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble ≤-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human Galectin-13 protein fragment (aa1-139) (exact sequence is proprietary)

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for LGALS13

Target: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Alternative Name: Galectin-13

Background:

Gal-13, GAL13, Galactoside-binding soluble lectin 13, Galectin-13, Galectin13, Lectin galactoside binding soluble 13, LGALS13, PLAC8, Placental protein 13 (PP13), Placental tissue protein 13

K-562 cells. Placenta or Spleen.

Molecular Weight: 16kDa (monomer), 32kDa (homodimer)

Gene ID: 29124, 23671

UniProt: Q9UHV8