Interferon gamma antibody (AA 1-166)

Catalog No. ABIN7858304

This Mouse Monoclonal antibody specifically detects Interferon gamma in IHC. It exhibits reactivity toward Human.

Quick Overview for Interferon gamma antibody (AA 1-166) (ABIN7858304)

Target: Interferon gamma (IFNG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Interferon gamma antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: IFNG-9012

Product Details anti-Interferon gamma Antibody

Binding Specificity: AA 1-166

Purpose: Interferon gamma (IFNG) Antibody

Specificity: Recognizes a protein of 20-25 kDa, identified as human interferon. This MAb is specific to human IFN-≥ and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-≥. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-±/≤ (type I interferon).

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-166) of human IFNG protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for Interferon gamma

Target: Interferon gamma (IFNG)

Alternative Name: Interferon gamma

Background:

AMCF1, Beta thromboglobulin like protein, CXC chemokine ligand 8 (CXCL8), Emoctakin, Granulocyte chemotactic protein 1 (GCP1), IFG, IFI, IFN Immune, IFN-gamma (IFNG), Interleukin 8, Interferon gamma, LECT, LUCT, Lymphocyte derived neutrophil activating factor, LYNAP, Macrophage Activating Factor (MAF), Monocyte derived neutrophil activating protein (MONAP), Monocyte derived neutrophil chemotactic factor (MDNCF), Neutrophil activating factor (NAF), Neutrophil activating peptide 1 (NAP1), Neutrophil activating protein 1 (NAP1), SCYB8, T cell chemotactic factor, T Cell Interferon

Human renal or testicular carcinoma.

Molecular Weight: 20-25kDa

Gene ID: 3458, 856

UniProt: P01579

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy