ADCY8 antibody (AA 1-200)

Catalog No. ABIN7865044

The Mouse Monoclonal anti-ADCY8 antibody is suitable to detect ADCY8 in samples from Human. It has been validated for IHC.

Quick Overview for ADCY8 antibody (AA 1-200) (ABIN7865044)

Target: ADCY8 (Adenylate Cyclase 8 (Brain) (ADCY8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADCY8 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: ADCY8-7573

Product Details anti-ADCY8 Antibody

Binding Specificity: AA 1-200

Purpose: ADCY8 (Adenylate Cyclase 8) Antibody

Specificity: Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008]

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human ADCY8 protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for ADCY8

Target: ADCY8 (Adenylate Cyclase 8 (Brain) (ADCY8))

Alternative Name: ADCY8

Background:

ADCY3, Adenylate cyclase type VIII, ATP pyrophosphate-lyase 8, Brain adenylate cyclase 8, Ca(2+)/calmodulin activated adenylyl cyclase, EC 4.6.1.1, HBAC1

Human brain tissue.

Molecular Weight: 140kDa

Gene ID: 114, 16874

UniProt: P40145

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma