EGFL7 antibody (AA 1-200)

Catalog No. ABIN7865252

The Mouse Monoclonal anti-EGFL7 antibody is suitable to detect EGFL7 in samples from Human. It has been validated for WB and IHC.

Quick Overview for EGFL7 antibody (AA 1-200) (ABIN7865252)

Target: EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EGFL7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: EGFL7-9499

Product Details anti-EGFL7 Antibody

Binding Specificity: AA 1-200

Purpose: EGFL7 (Tumor Angiogenesis Marker) Antibody

Specificity: Epidermal growth factor (EGF) repeat-containing proteins constitute an expanding family of proteins that are involved in several cellular activities, such as blood coagulation, fibrinolysis, cell adhesion and neural and vertebrate development. A human EGF repeat superfamily member that maps to human chromosome X, EGFL6, encodes a predicted signal peptide suggesting that it is secreted. EGFL6 is expressed in brain and lung tumors and fetal tissues but is generally absent from normal adult tissues. EGFL7 is a secreted protein that regulates vascular tubulogenesis in vivo. In vitro, EGFL7 inhibits platelet-derived growth factor induced smooth muscle cell migration and promotes adhesion of endothelial cells to the substrate. EGFL7 is expressed specifically by endothelial cells of the heart, lung and kidney.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human EGFL7 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for EGFL7

Target: EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))

Alternative Name: EGFL7

Background:

MEGF7

293T cells. Human endometrium, tonsil, kidney or placenta.

Molecular Weight: 30kDa

Gene ID: 51162

UniProt: Q9UHF1