HSD17B13 antibody (AA 1-200)

Catalog No. ABIN7865380

The Mouse Monoclonal anti-HSD17B13 antibody is suitable to detect HSD17B13 in samples from Human. It has been validated for WB and IHC.

Quick Overview for HSD17B13 antibody (AA 1-200) (ABIN7865380)

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSD17B13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: HSD17B13-13108

Product Details anti-HSD17B13 Antibody

Binding Specificity: AA 1-200

Purpose: HSD17B13 / Hydroxysteroid 17-beta dehydrogenase 13 Antibody

Specificity: Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) is an engyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human HSD17B13 protein (exact sequence is proprietary)

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for HSD17B13

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Alternative Name: HSD17B13

Background:

7-beta hydroxysteroid dehydrogenase, 17-beta-HSD 13, hepatic retinol/retinal dehydrogenase, short chain dehydrogenase/reductase family 16C member 3, short-chain dehydrogenase/reductase 9

Human liver, ovary, kidney, brain or bone marrow.

Molecular Weight: 30kDa

Gene ID: 345275

UniProt: Q7Z5P4