S100A5 antibody (AA 1-92)

Catalog No. ABIN7864421

The Mouse Monoclonal anti-S100A5 antibody is suitable to detect S100A5 in samples from Human. It has been validated for IHC.

Quick Overview for S100A5 antibody (AA 1-92) (ABIN7864421)

Target: S100A5 (S100 Calcium Binding Protein A5 (S100A5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This S100A5 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: S100A5-7472

Product Details anti-S100A5 Antibody

Binding Specificity: AA 1-92

Purpose: S100A5 Antibody

Specificity: The S-100 proteins are small calcium-binding proteins which display different expression patterns in human tissues. Some S-100 proteins are associated with tumor development and the metastatic behavior of tumors. S-100A5 (S100 calcium binding protein A5) is a 92 amino acid protein that belongs to the S-100 family. Containing two EF-hand domains, S-100A5 binds calcium, zinc and copper. One subunit can simultaneously bind two calcium ions or two copper ions plus one zinc ion. Calcium and copper ions compete for the same binding sites on the S-100A5 protein. The S-100A5 protein is expressed in very restricted regions of the adult brain. The S-100A5 gene is conserved in chimpanzee, dog, cow, mouse and rat, and maps to human chromosome 1q21.3. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. Due to the clustered organization of the S-100 proteins a new logical nomenclature based on their physical arrangement on the chromosome has been described, with S-100A1 being closest to the telomere and S-100A9 being closest to the centromere.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-92) of human S100A5 protein (exact sequence is proprietary)

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for S100A5

Target: S100A5 (S100 Calcium Binding Protein A5 (S100A5))

Alternative Name: S100A5

Background:

Protein S-100D, Protein S100-A5, S100 calcium binding protein A5, S100 calcium-binding protein A5, S100D, S100D9

Human brain or colon.

Molecular Weight: 11kDa

Gene ID: 6276, 2960

UniProt: P33763

Pathways: S100 Proteins