Recombinant S100A12 antibody (AA 1-95)

Catalog No. ABIN7865008

This Rabbit Monoclonal antibody specifically detects S100A12 in IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant S100A12 antibody (AA 1-95) (ABIN7865008)

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This S100A12 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: S100A12-8952R

Product Details anti-S100A12 Antibody

Binding Specificity: AA 1-95

Purpose: Recombinant S100A12 / CGRP Antibody

Specificity: The family of EF-hand type Ca2+-binding proteins includes Calbindin (previously designated vitamin D-dependent Ca2+-binding protein), S-100 ± and ≤, Calgranulins A (also designated MRP8), B (also designated MRP14) and C (S-100 like proteins) and the parvalbumin family members, including parvalbumin ± and parvalbumin ≤ (also designated oncomodulin). Calbindin, S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S-100 ± and ≤ are present in a variety of other tissues, and Calbindin is present in intestine and kidney. Parvalbumin ± is also found in fast-contracting/relaxing skeletal muscle fibers and parvalbumin ≤ is found in many tumor tissues as well as in the organ of Corti. Calbindin, S-100 proteins and parvalbulmins have all been detected in leydig cells and the testis. These proteins are thought to play a role in hormone production and spermatogenesis. Calgranulin is expressed in macrophages and epithelial cells.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-95) of human S100A12 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for S100A12

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Alternative Name: S100A12

Background:

CAAF1, CAGC, Calcitermin, Calcium-binding protein in amniotic fluid 1, Calgranulin C, Calgranulin-related protein, CGRP, EN-RAGE, Extracellular newly identified RAGE-binding protein, migration inhibitory factor-related protein 6, MRP6, Neutrophil S100 protein, p6, Protein S100 A12, S100 calcium-binding protein A12

Monocytes and lymphocytes.

Molecular Weight: 11kDa

Gene ID: 6283, 19413

UniProt: P80511

Pathways: Toll-Like Receptors Cascades, S100 Proteins