Recombinant krt57.L antibody (AA 100-200)

Catalog No. ABIN7858930

The Mouse Monoclonal anti-krt57.L antibody (Clone rKRTL-6616) (ABIN7858930) specifically detects krt57.L in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant krt57.L antibody (AA 100-200) (ABIN7858930)

Target: krt57.L (Keratin 57 L Homeolog (krt57.L))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This krt57.L antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: RKRTL-6616

Product Details anti-krt57.L Antibody

Binding Specificity: AA 100-200

Purpose: Recombinant Cytokeratin, Type I (Epithelial Marker) Antibody

Specificity: The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation. This antibody can detect high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19. It usually used in a cytokeratin cocktail with type II cytokeratin antibody.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Synthetic peptide corresponding to Type I Cytokeratins residues within aa100-200 of Type I Cytokeratins

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for krt57.L

Target: krt57.L (Keratin 57 L Homeolog (krt57.L))

Alternative Name: Cytokeratin, Type I

Background:

K1B, KRT1B, K77, CK-1B, Keratin 1B, Keratin-77, Cytokeratin-1B

Skin or squamous cell carcinoma.

Molecular Weight: 60/53/51/45/40kDa

Gene ID: 374454, 334989

UniProt: Q7Z794