MUC13 antibody (AA 100-300)

Catalog No. ABIN7859030

This Mouse Monoclonal antibody specifically detects MUC13 in IHC. It exhibits reactivity toward Human.

Quick Overview for MUC13 antibody (AA 100-300) (ABIN7859030)

Target: MUC13 (Mucin 13, Cell Surface Associated (MUC13))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC13 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: MUC13-13113

Product Details anti-MUC13 Antibody

Binding Specificity: AA 100-300

Purpose: MUC13 / Mucin 13 Antibody

Specificity: Mucins are epithelial glycoproteins with a high content of clustered oligosaccharides that are O-glycoside linked to tandem repeat peptides rich in threonine, serine and proline. Mucin 13 (MUC13), also designated downregulated in colon cancer 1 (DRCC1), is an epithelial and hemopoietic type I membrane protein that undergoes secretion and influences gastrointestinal mucosa levels. It is most abundant in epithelial tissues of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. Mucin 13 is a good differentiation marker for gastrointestinal mucosa and may also indicate certain gastric tumors. It localizes to the apical membrane of both columnar and goblet cells in the gastrointestinal tract, and within goblet cell thecae. Mucin 13 is a cleaved protein, and the b subunit, containing the cytoplasmic tail, can homodimerize.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa100-300) of human MUC13 protein (exact sequence is proprietary)

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for MUC13

Target: MUC13 (Mucin 13, Cell Surface Associated (MUC13))

Alternative Name: MUC13

Background:

DRCC1, MUC-13

Human colon or small intestine.

Molecular Weight: 58kDa

Gene ID: 56667, 514227

UniProt: Q9H3R2