Recombinant Uroplakin 3B antibody (AA 100-300)

Catalog No. ABIN7859042

This Rabbit Monoclonal antibody specifically detects Uroplakin 3B in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant Uroplakin 3B antibody (AA 100-300) (ABIN7859042)

Target: Uroplakin 3B (UPK3B)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Uroplakin 3B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Clone: UPK3B-8768R

Product Details anti-Uroplakin 3B Antibody

Binding Specificity: AA 100-300

Purpose: Recombinant Uroplakin 3B (UPK3B) (Marker of Mesothelial & Umbrella Cells) Antibody

Specificity: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. 79oΩ

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 100-300) of human Uroplakin 3B (UPK3B) protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for Uroplakin 3B

Target: Uroplakin 3B (UPK3B)

Alternative Name: Uroplakin 3B

Background:

FLJ32198, MGC10902, p35, UP3b, UPIIIb, UPK3B, UPK3B_HUMAN, uroplakin 3B, Uroplakin IIIb, Uroplakin-3b

Human urinary bladder.

Molecular Weight: 32kDa

Gene ID: 105375355, 488861

UniProt: Q9BT76