FOXI1 antibody (AA 104-258)

Catalog No. ABIN7864714

The Mouse Monoclonal anti-FOXI1 antibody is suitable to detect FOXI1 in samples from Human. It has been validated for WB, IF, IHC and FACS.

Quick Overview for FOXI1 antibody (AA 104-258) (ABIN7864714)

Target: FOXI1 (Forkhead Box I1 (FOXI1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXI1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: PCRP-FOXI1-1C4

Product Details anti-FOXI1 Antibody

Binding Specificity: AA 104-258

Purpose: FOXI1 / Forkhead Box I1 (Transcription Factor) Antibody

Specificity: FOXL1 is a 337 amino acid protein encoded by the mouse gene FOXL1. FOXL1 belongs to the forkhead family and contains one forkhead DNA-binding domain. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1-deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyer's patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the Adenomatous Polyposis Coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa104-258) of human FOXL1 protein (exact sequence is proprietary)

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for FOXI1

Target: FOXI1 (Forkhead Box I1 (FOXI1))

Alternative Name: FOXI1

Background:

FKHL10, FREAC6, JFJ-3, FKH6, FKH11, Forkhead box protein L1, Forkhead related transcription factor, FREAC7

HeLa or U87 cells. Ubiquitous tissue expression.

Molecular Weight: 36-41kDa

Gene ID: 2299, 87236