FOXL1 antibody (AA 104-258)

Catalog No. ABIN7862814

This Mouse Monoclonal antibody specifically detects FOXL1 in WB, IHC, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for FOXL1 antibody (AA 104-258) (ABIN7862814)

Target: FOXL1 (Forkhead Box L1 (FOXL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-FOXL1-1F8

Product Details anti-FOXL1 Antibody

Binding Specificity: AA 104-258

Purpose: FOXL1 / Forkhead Box Protein L1 (Transcription Factor) Antibody

Specificity: FOXL1 is a 337 amino acid protein encoded by the mouse gene FOXL1. FOXL1 belongs to the forkhead family and contains one forkhead DNA-binding domain. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1-deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyer's patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the Adenomatous Polyposis Coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa104-258) of human FOXL1 protein (exact sequence is proprietary)

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for FOXL1

Target: FOXL1 (Forkhead Box L1 (FOXL1))

Alternative Name: FOXL1

Background:

FKHL10, FREAC6, JFJ-3, FKH6, FKH11, Forkhead box protein L1, Forkhead related transcription factor, FREAC7

HeLa or U87 cells.Ubiquitous tissue expression.

Molecular Weight: 36-41kDa

Gene ID: 2299, 87236

UniProt: Q12951