LIN28A antibody (AA 134-187)

Catalog No. ABIN7859106

The Mouse Monoclonal anti-LIN28A antibody is suitable to detect LIN28A in samples from Human. It has been validated for FACS.

Quick Overview for LIN28A antibody (AA 134-187) (ABIN7859106)

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LIN28A antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: PCRP-LIN28A-1E2

Product Details anti-LIN28A Antibody

Binding Specificity: AA 134-187

Purpose: LIN28A (Transcription Factor) Antibody

Specificity: LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein synthesis efficiency and binds to the growth and differentiation factor IGF-II.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa134-187) of human LIN28A protein

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for LIN28A

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Alternative Name: LIN28A

Background:

CSDD1, FLJ12457, LIN-28, LIN28, ZCCHC1

HeLa or U87 cells.

Molecular Weight: 22.74kDa

Gene ID: 79727, 86154

UniProt: Q9H9Z2

Pathways: Stem Cell Maintenance