OVOL2 antibody (AA 175-275)

Catalog No. ABIN7859282

This Mouse Monoclonal antibody specifically detects OVOL2 in IHC. It exhibits reactivity toward Human.

Quick Overview for OVOL2 antibody (AA 175-275) (ABIN7859282)

Target: OVOL2 (Ovo-Like 2 (OVOL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This OVOL2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: OVOL2-6776

Product Details anti-OVOL2 Antibody

Binding Specificity: AA 175-275

Purpose: OVOL2 / CRE-Bpa Antibody

Specificity: The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB-3 and Luman), CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/ CREB proteins bind CREs in their homodimeric form, they can also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A- mediated CREB phosphorylation induces association with a nuclear protein designated CBP (CREB-binding protein), which may represent a CREB coactivator. CRE-BPa is a nuclear protein that binds DNA as a homodimer but can also form a heterodimer with ATF-2 or Jun.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa175-275) of human OVOL2 protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for OVOL2

Target: OVOL2 (Ovo-Like 2 (OVOL2))

Alternative Name: OVOL2

Background:

bA504H3.3, hOvo2, Ovo like 2, ovo-like zinc finger 2 (OVOL2), Transcription factor Ovo-like 2, Zinc finger protein 339 (ZNF339)

HeLa|U87 or K562 cells.

Molecular Weight: 69.1kDa

Gene ID: 58495, 437075

UniProt: Q9BRP0

Pathways: Tube Formation