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Recombinant PD-L1 antibody (AA 190-290)

This Mouse Monoclonal antibody specifically detects PD-L1 in IHC. It exhibits reactivity toward Human.

Catalog No. ABIN7864465

$640.46

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Quick Overview for Recombinant PD-L1 antibody (AA 190-290) (ABIN7864465)

Target

See all PD-L1 Antibodies

PD-L1 (CD274 (PD-L1))

Antibody Type

Recombinant Antibody

Reactivity

Human

Host

Mouse

Clonality

Monoclonal

Conjugate

This PD-L1 antibody is un-conjugated

Application

Immunohistochemistry (IHC)

Clone

RPDL1-8825

Discover our top product PD-L1 Primary Antibody

Binding Specificity
51

29

29

19

16

15

13

13

13

11

8

7

7

6

6

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 190-290

Purpose

Recombinant PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Antibody

Specificity

PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.

Purification

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen

Recombinant fragment (around aa190-290) of human CD274 protein (exact sequence is proprietary)

Isotype

IgG1, kappa
anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 Reactivity: Human WB, FACS, ELISA, IF Host: Goat Polyclonal unconjugated

anti-CD274 (PD-L1) (C-Term) antibody
PD-L1 Reactivity: Human WB, FACS, IHC, IP, IF (p), IF/ICC, mIF Host: Rabbit Monoclonal BLR020E unconjugated Recombinant Antibody

anti-CD274 (PD-L1) (AA 39-191) antibody
PD-L1 Reactivity: Human, Mouse WB, FACS, IHC, ELISA, IF Host: Mouse Monoclonal PDL1-2746 unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 Reactivity: Human FACS, IHC, ELISA Host: Mouse Monoclonal 6D9A2 unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 Reactivity: Human WB, FACS, IHC, ELISA, IF Host: Mouse Monoclonal 9B5F4 unconjugated

anti-CD274 (PD-L1) (AA 48-290) antibody
PD-L1 Reactivity: Mouse WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 34-241) antibody
PD-L1 Reactivity: Mouse WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 7D2A10 unconjugated

anti-CD274 (PD-L1) (C-Term) antibody
KO Validated PD-L1 Reactivity: Human WB, FACS, ICC, IF, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-234) antibody
PD-L1 Reactivity: Human WB, ICC, IF Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Concentration

200 μg/mL

Buffer

Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Storage Comment

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Target

PD-L1 (CD274 (PD-L1))

Alternative Name

PD-L1

Background

B7 homolog 1, B7-H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1
Human placenta|spleen or tonsil tissue.

Molecular Weight

37-50kDa

Gene ID

29126, 521989

UniProt

Q9NZQ7

Pathways

Cancer Immune Checkpoints