BTBD9 antibody (AA 200-400)

Catalog No. ABIN7864599

This Mouse Monoclonal antibody specifically detects BTBD9 in IHC. It exhibits reactivity toward Human.

Quick Overview for BTBD9 antibody (AA 200-400) (ABIN7864599)

Target: BTBD9 (BTB (POZ) Domain Containing 9 (BTBD9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BTBD9 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: BTBD9-7501

Product Details anti-BTBD9 Antibody

Binding Specificity: AA 200-400

Purpose: BTBD9 Antibody

Specificity: BTBD9 (BTB/POZ domain-containing protein 9) is a 612 amino acid protein that contains one BTB/POZ domain and one BACK (BTB/Kelch associated) domain. The BTB/POZ domain mediates homomeric and heteromeric POZPOZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including Bcl-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD9 may play a role in transcription regulation. Genetic variations in the gene that encodes BTBD9 have been associated with susceptibility to restless legs syndrome type 6 (RLS6), a condition characterized by an uncontrollable urge to move the legs while resting.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa200-400) of human BTBD9 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for BTBD9

Target: BTBD9 (BTB (POZ) Domain Containing 9 (BTBD9))

Alternative Name: BTBD9

Background:

BTB/POZ domain-containing protein 9

Human fallopian tube|lung or lymph node.

Molecular Weight: 69kDa

Gene ID: 114781, 603858

UniProt: Q96Q07

Pathways: Transition Metal Ion Homeostasis