IL18RAP antibody (AA 200-400)

Catalog No. ABIN7864577

The Mouse Monoclonal anti-IL18RAP antibody (Clone IL18RAP-7771) (ABIN7864577) specifically detects IL18RAP in IHC. The antibody is reactive with Human samples.

Quick Overview for IL18RAP antibody (AA 200-400) (ABIN7864577)

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL18RAP antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: IL18RAP-7771

Product Details anti-IL18RAP Antibody

Binding Specificity: AA 200-400

Purpose: IL18RAP / CD218b Antibody

Specificity: The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa200-400) of human IL18RAP protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for IL18RAP

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Alternative Name: IL18RAP

Background:

IL18RAP, Accessory protein like, AcPL, CD218 antigen-like family member B, CDw218b, IL 18RAcP, IL 1R accessory protein like, IL 1R7, IL 1RAcPL, IL18R Beta, IL18RAP, IL18Rbeta, Interleukin 18 receptor accessory protein, Interleukin-1 receptor 7, Interleukin-18 receptor beta chain

adrenal gland or colon.|Human spleen|lung

Molecular Weight: 68kDa

Gene ID: 8807, 158315

UniProt: O95256