Apolipoprotein D antibody (AA 21-119)

Catalog No. ABIN7862976

The Mouse Monoclonal anti-Apolipoprotein D antibody (Clone APOD-3414) (ABIN7862976) specifically detects Apolipoprotein D in IHC. The antibody is reactive with Human samples.

Quick Overview for Apolipoprotein D antibody (AA 21-119) (ABIN7862976)

Target: Apolipoprotein D (APOD)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Apolipoprotein D antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: APOD-3414

Product Details anti-Apolipoprotein D Antibody

Binding Specificity: AA 21-119

Purpose: Apolipoprotein D / APO-D Antibody

Specificity: Lipids, such as phospholipids, triacylglycerols and cholesterol, are weakly soluble in aqueous solution and therefore are transported by circulation as components of lipoproteins. Lipoproteins are globular particles that consist of a non-polar core of triacylglycerols and cholesteryl esters surrounded by phospholipid, cholesterol and an amphiphilic coating of protein, known as apolipoproteins (apo). These complexes allow the dissolution and shuttling of their non-polar lipid components. At least nine different apolipoproteins are distributed in significant amounts in different human lipoproteins. Apolipoprotein D (apoD) is a member of the lipocalin superfamily of transporter proteins that bind small hydrophobic molecules, including arachidonic acid (AA). The ability of apoD to bind AA implicates it in pathways associated with membrane phospholipid signal transduction and metabolism. apoD expression has been shown to correlate both with cell cycle arrest and with prognosis in several types of malignancy, including central nervous system astrocytomas and medulloblastomas.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Human recombinant APOD protein fragment (around aa21-119) (exact sequence is proprietary)

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Apolipoprotein D

Target: Apolipoprotein D (APOD)

Alternative Name: Apolipoprotein D

Background:

APO-D protein

Human liver, kidney or spleen.

Molecular Weight: 30kDa

Gene ID: 347, 522555

UniProt: P05090

Pathways: Platelet-derived growth Factor Receptor Signaling