USF2 antibody (AA 220-346)

Catalog No. ABIN7859555

This Mouse Monoclonal antibody specifically detects USF2 in IHC, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for USF2 antibody (AA 220-346) (ABIN7859555)

Target: USF2 (Upstream Transcription Factor 2, C-Fos Interacting (USF2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This USF2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-USF2-1A7

Product Details anti-USF2 Antibody

Binding Specificity: AA 220-346

Purpose: USF2 Antibody

Specificity: The ubiquitously expressed cellular upstream stimulatory factor (USF) consists of USF-1 and USF-2 polypeptides which independently exhibit site-specific DNA binding and are members of the c-Myc-related family of regulatory factors containing helix-loop-helix domains. USF also contains a leucine repeat that is required for efficient DNA binding. USF was originally identified as an upstream stimulatory factor that binds the core sequence CACGTG in the adenovirus late promoter. These findings, together with the demonstration of cooperative interaction between USF and the initiatorbinding protein, TFII-I, raises the possibility of a more general involvement of USF in transcriptional regulation. While expression of both USF-1 and USF-2 species is ubiquitous, different ratios of USF homo- and heterodimers are found in different cell types.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (aa220-346) of human USF2 protein

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for USF2

Target: USF2 (Upstream Transcription Factor 2, C-Fos Interacting (USF2))

Alternative Name: USF2

Background:

bHLHb12, FIP

HeLa cells.

Molecular Weight: 44kDa

Gene ID: 7392, 454534

UniProt: Q15853